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Description

JOB CODE: XNOPZ

CCHMC SALARY GRADE:13

Scope: 5+ direct/indirect reports or sole responsibility for a site/line of business

Cincinnati Children's Hospital is establishing a state-of-the-art Gnotobiotic service capability offered from the Division of Veterinary Services. We are seeking a highly motivated person to be its Operations Manager. The Manager will be responsible for overseeing the daily operation and management of the service line/facility and establishing all necessary Standard Operating Procedures with emphasis on quality control and the preservation of isolators free of contaminants. The Manager will also interact closely with multiple faculty researchers and their laboratory staff from Cincinnati Children's and University of Cincinnati. The ideal candidate will have significant experience in successfully deriving germ-free mice, establishing specific gnotobiotic models, and a strong background in small animal husbandry specific to maintaining mice in sterile isolators. A successful candidate will have management experience, strong organizational skills, and a solid understanding of research design and implementation are integral. They will also have demonstrated the ability to work professionally and collaboratively with colleagues and customers, and a strong commitment to personal responsibility and value for safety. This position is subject to and will be expected to comply with all applicable institutional policies and procedures.

Core Duties

• Oversee the daily operational and scientific activities of the facility
• Create germ-free and gnotobiotic murine animal models
• Work with veterinary team and facility staff to establish detailed Standard Operating Procedures, and LEAN efficiencies for all operational tasks
• Establish partnerships with transgenic, pathology, genomics, and microbiological cores for required services in quality control of gnotobiotic models
• Train and supervise animal technicians tasked with isolator use, preparation of sterile supplies, and all aspects of animal care and husbandry
• Ensure the facility remains compliant with all regulatory entities such as IACUC, IBC, EHS and AAALAC standards, and internal DVS husbandry and welfare standards
• Ensure maintenance of the facility including management of chemical inventory, safety, recordkeeping, and laboratory equipment procurement
• Participation as a member of DVS Operations Management Team for cross-training, oversight of facility activities, and carrying out Division goals
• Interact with facility users on experimental design and procedures that require use of gnotobiotic or germ-free mice, such as analyzing and interpreting results and contributing to the preparation of manuscripts for publication, especially methods and results sections

Qualifications

EDUCATION/EXPERIENCE

Required:
???Bachelor degree or equivalent combination of education and experience
??? 5 years of experience in a related discipline OR extensive experience operating a gnotobiotic facility

Preferred:

Masters degree in a related field

Unique Skills:

• Experience in mouse husbandry using germ-free isolators, including monitoring mouse conditions and sterilization of materials for introduction into germ-free isolators
• Experience in creation of germ-free and gnotobiotic murine animal models
• Experience in all aspects of local and federal animal regulatory guidelines and practices
• Complete understanding of basic scientific principles
• Skilled with use of computers, standard computer programs, and database applications
• Strong analytical skills and sound judgment
• Experience in maintaining detailed records of experiments and outcomes
• Proven managerial skills
• Excellent organizational skills, ability to accurately complete detailed work
• Proficiency in rodent breeding management and handling techniques, including oral gavage, blood collection, and aseptic surgery
• Experience with basic microbial culture methods
• Experience deriving germ-free mice