Postdoctoral Research Fellow - Rho Signaling in Tumor Immune Cell Invasion - Guo Lab
Cincinnati Children's Hospital Medical Center
Location: Cincinnati, Ohio
Academic / Research
Internal Number: 118972
Fukun Guo, PhD, has an immediate opening in his lab for a postdoctoral Research Fellow. Dr. Guo's lab investigates the role and mechanisms of Rho family GTPases in T lymphocyte development and function, particularly in the context of tumor immune evasion. Candidates need to have excellent skills in flow cytometry and animal handling. Experience in Molecular and Cellular biology, Immunology, and Cancer Biology is required. Expertise in T cell biology, tumor immunology/cancer immunotherapy, and/or bioinformatics is a plus.
About Cincinnati Children's
Cincinnati Children's Hospital Medical Center is a premier pediatric research institution with over 900 diverse and productive faculty members. Here, researchers work collaboratively across specialties and divisions to address some of the biggest challenges we face today in improving child health. A strong network of research support services and facilities, along with institutional commitment to research, push our team of faculty, postdocs and support staff to explore the boundaries of what is possible, leading to significant breakthroughs. We are driven by our mission to improve child health and transform the delivery of care through fully integrated, globally recognized research, education and innovation.
MAJOR DUTIES AND RESPONSIBILITIES: 1. Design, execute, and record laboratory experiments; apply standard scientific protocols to experiments, research, and improve current methods and evaluate innovative techniques. 2. Draft, write, and edit scientific reports, papers, journal articles, and abstracts. 3. Design and perform experiments and record data according to research protocol. Independently reproduce, evaluate, research, and improve techniques currently used. Adapt new methods to existing procedures and modify current experiments through scientific knowledge and intuition. Maintain accurate and detailed records of all laboratory work and experiments. 4. Develop, set-up, and verify new procedures in the laboratory. Standardize and establish new published procedures; evaluate innovative techniques. Develop new assays and new protocols; design formats. 5. Discuss relevant insights about experimental results with Faculty and provide useful recommendations and analysis. 6. Maintain an integral role in the laboratory's meetings, presentations, and publications. Present information on research and laboratory work to others at laboratory meetings, journal clubs, and seminars. 7. Troubleshoot and correct erroneous results or problems with laboratory equipment. Maintain and repair equipment; monitor proper use by personnel. 8. Maintain optimal protocol and assay accuracy by conducting regular quality and reproducibility checks. 9. Assist in preparing, writing, and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests; track funding, maintain accurate balance, and resolve any discrepancies. 10. Follow policies and procedures governing the handling of confidential information as defined by Cincinnati Children's mission and applicable laws and regulations. Ensure timeliness, accuracy, availability, and security of information. 11. Perform routine procedures, including the collection and analysis of research data, which may affect decisions regarding future patient care. 12. Provide services in a manner to be regularly and conveniently available to meet the needs of Cincinnati Children's research initiatives as determined by department management and Cincinnati Children's governing body. 13. Maintain currency in field through continuing education, literature and seminars. Implement this knowledge into the Department. 14. Recommend approaches for improvement activities, recommend and perform new processes, collect and measure data, develop processes based on performance, and communicate results. 15. Ensure that work areas are organized and present a safe, accessible, effective and efficient environment. Manage attendance at required Cincinnati Children's training sessions, including radiation safety, laboratory safety, bloodborne pathogens, and OSHA. Comply with Infection Control policies and procedures. 16. Participate in establishing job requirements and goals; perform duties at the desired level of competency. 17. Understand, adhere to, and model Core Standards as defined organizationally and specifically within the department/unit. 18. Perform other duties as assigned.
Required: A PhD, MD, or equivalent doctoral degree. Candidates need to have excellent skills in flow cytometry and animal handling. Experience in Molecular and Cellular biology, Immunology, and Cancer Biology is required.
Preferred: Expertise in T cell biology, tumor immunology/cancer immunotherapy, and/or bioinformatics is a plus.
At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better, and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children’s.