We are seeking a Postdoctoral Research Associate to join our NIH-funded laboratory that conducts basic research in the neurophysiology of general anesthesia. Our group utilizes a combination of multisite intracranial recordings, optogenetics, chemogenetics (DREADDs) and touchscreen-based cognitive testing in rodents to elucidate the neural circuit mechanisms of anesthetic-induced unconsciousness. In addition, we are studying the role of brainstem and midbrain arousal pathways in restoring consciousness and cognition after general anesthesia.
With appropriate supervision and support, responsibilities of the Postdoctoral Research Associate will include: designing experiments, performing surgical procedures in anesthetized rodents, performing behavioral experiments to test for recovery of consciousness and cognition, data analysis, and manuscript preparation.
Must be meticulous and detail-oriented, and possess strong communication and writing skills. Demonstrated ability to communicate research findings in the form of peer-reviewed publications and oral presentations is required. Must be willing to work with rodents.
Internal Number: 20191017
About Massachusetts General Hospital / Harvard Medical School
The Solt Laboratory studies the neural circuit mechanisms of general anesthesia using a systems neuroscience approach. We combine optogenetics, chemogenetics, neurophysiological recordings, and touchscreen-based cognitive testing in rodents to elucidate the neural circuits that govern anesthetic-induced unconsciousness, as well as recovery of consciousness and cognition after general anesthesia. Our long-term goal is to make general anesthesia safer by developing new therapeutic options for common clinical problems such as delayed emergence from general anesthesia, post-operative delirium, and cognitive dysfunction.
Please visit www.soltlab.com to learn more about our laboratory.